ABSTRACT
Introduction: The adenexa are part of skin andcomprised of sebaceous glands, sweat glands and hairfollicles. Skin adenexal tumors are rare in occurrenceand precise classification of these neoplasms is difficult.Benign tumors are more common than malignanttumors. Current study aimed to know the histopathologyof skin adenexal neoplasm and to correlate with age,gender, loacation and type of differentiation.Material and methods: A prospective study of 57histopathologically confirmed cases of skin adenexaltumors was carried out in Department of Pathology. Inthis study biopsies were received in 10% formalin andstained by routine haematoxylin and eosin stain. Nonneoplastic conditions were excluded from the study.Results: Out of the 57 cases of skin adenexal tumorsstudied 55 (96.5% ) were benign and 2 (3.5% ) weremalignant with a male: female ratio of 1:1.3. The mostfrequent group of tumors were of eccrine/apocrineorigin 28/57 (49.1%) followed by follicular origin(38.6%) 22/57 and sebaceous origin 7/57 (12.9%).Pilomatrixoma was the most common benign tumorand sebaceous carcinoma was the only malignant tumorencountered in the study. Most common age groupaffected range from 41-60 years and mean age observedwas 45 years. Head and neck (47.5%, 27/57) was themost common site involved in both males and femaleswith a predominance in the facial region.Conclusion: Skin adenexal tumors (SAT) are very rareand the classification of these tumours is complex. Thesetumors are usually missed clinically and histopathologyproves to be the gold standard for diagnosis of theseneoplasms.
ABSTRACT
Introduction: Pancytopenia is a very common consequenceof many haematological diseases with extensive differentialdiagnosis. It is described as the deficiency of all three cellularelements of blood resulting in anemia and leucopenia andthrombocytopenia. The severity and underlying pathologydetermines the management and prognosis. Bone marrowexamination is an effective way of evaluating various causesof pancytopenia along with other clinical, haematologicalfindings.Material and methods: In this prospective study, a total60 patients presenting with pancytopenia on initial work uprequiring bone marrow examination were studied along withtheir relevant clinical history, examination findings, routinehaematological findings.Results: Among 60 cases studied, age of patients ranged from1-85 years with slight male predominance. Most commonage group involve was 11-30 years. Most of the patientspresented with generalised weakness, pallor, fever. Dimorphicanemia was the predominant blood picture. The commonestmarrow finding was hypercellularity with megaloblasticerythropoiesis. The commonest cause of pancytopenia wasmegaloblastic anemia 62.79% followed by sub/aleukemicleukemia 25.57%.Conclusions: Bone marrow examination can diagnosedmajority of cases of pancytopenia along with comprehensiveclinical and haematological study. It is also helpful in planningfurther investigations and management.